Human PHD finger protein 3 (PHF3) ELISA Kit
715€ (96 tests)
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name
Human PHD finger protein 3 (PHF3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx538666
tested applications
ELISA
Description
Human PHD finger protein 3 (PHF3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human PHD finger protein 3 (PHF3) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | PHD finger protein 3 (PHF3) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q92576 |
| OMIM | 607789 |
| Alias | PHF3, KIAA0246 |
| Background | Elisa kits for PHF3 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
PHF3 is a chromatin-binding protein containing a PHD domain that mediates the recognition of methylated histones, particularly H3K4me3, to regulate transcriptional activation and RNA polymerase II-dependent transcription. It serves as a transcriptional regulator by linking histone modifications to transcription elongation, ensuring precise gene expression during cellular proliferation and differentiation. PHF3 is expressed in neuronal and hematopoietic tissues, where it contributes to neurodevelopment, DNA damage repair, and cell survival. It is also involved in tumor suppression, where it stabilizes chromatin structure and controls the expression of growth-regulating genes. Dysregulation of PHF3 is linked to neurodevelopmental disorders and cancers, where its loss of function disrupts transcriptional regulation and genome stability. Knockout studies reveal defects in transcription elongation, impaired DNA repair, and disrupted cellular differentiation, underscoring its critical role in transcriptional fidelity, chromatin regulation, and cellular homeostasis.
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Human PHD finger protein 3 (PHF3) ELISA Kit
Human PHD finger protein 3 (PHF3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human PHD finger protein 3 (PHF3) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Ver Producto