Human P2RY2 (P2Y purinoceptor 2) ELISA Kit
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Product specifications
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 23.438-1500pg/ml |
| Sensitivity | 14.063pg/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | P41231 |
| Alias | P2RY2,ATP receptor,P2U purinoceptor 1,P2Y ATP receptor 2,P2Y purinoceptor 2,purinergic receptor P2Y,HP2U, P2RU1, P2U, P2U1, P2UR, P2Y2 |
| Background | Elisa kits for P2RY2 |
| Status | RUO |
P2RY2 is a G protein-coupled receptor activated by ATP and UTP, serving as a key regulator of cellular responses to extracellular nucleotides. It is widely expressed in epithelial cells, endothelial cells, and immune cells, where it couples to Gq proteins, activating phospholipase C (PLC), increasing intracellular calcium, and modulating cytoskeletal dynamics and ion transport. P2RY2 plays a critical role in regulating inflammation, wound healing, and fluid secretion. In the respiratory tract, P2RY2 mediates mucus secretion and airway hydration, making it a therapeutic target for cystic fibrosis and chronic obstructive pulmonary disease (COPD). In addition, P2RY2 is involved in vascular remodeling, angiogenesis, and immune cell recruitment during tissue repair and inflammation. Dysregulation of P2RY2 contributes to inflammatory diseases, cardiovascular dysfunction, and fibrosis. P2RY2 agonists and antagonists are being explored for their potential in treating respiratory disorders, wound healing, and chronic inflammatory conditions.
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P2RY2 Antibody is a Rabbit Polyclonal antibody against P2RY2. The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene.
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