Human Oxysterols Receptor LXR-Alpha (NR1H3) ELISA Kit

Este producto es parte de NR1H - nuclear receptor subfamily 1 group H member
Human Oxysterols Receptor LXR-Alpha (NR1H3) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

537.5€ (96 tests)

Elisa Kits NR1H3

proveedor

Abbexa

reference

abx251397

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Oxysterols Receptor LXR-Alpha (NR1H3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Oxysterols Receptor LXR-Alpha (NR1H3) concentrations in Tissue homogenates, cell lysates and other biological fluids.


Background

Nuclear receptor subfamily 1 group H member 3 (NR1H3), also known as LXRβ (liver X receptor beta), is another member of the LXR family of nuclear receptors involved in regulating lipid and cholesterol metabolism NR1H3 is highly expressed in tissues like the liver, intestine, and adipose tissue, where it helps regulate the expression of genes that control cholesterol efflux, lipid storage, and glucose metabolism LXRβ also plays a role in regulating the immune system, particularly in macrophages, where it modulates the inflammatory response and contributes to the resolution of inflammation It helps maintain metabolic balance by controlling lipid homeostasis and by influencing glucose metabolism and insulin sensitivity Dysregulation of NR1H3 has been implicated in conditions such as type 2 diabetes, obesity, and cardiovascular diseases, where abnormal lipid metabolism and inflammation contribute to disease progression LXRβ is also a potential drug target for the treatment of atherosclerosis, metabolic disorders, and inflammatory diseases

Características del producto

category

ELISA Kits


immunogen target

Oxysterols Receptor LXR-Alpha (NR1H3)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


sensitivity

0.1 ng/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


alias

LXRA,LXR-a,RLD-1,Oxysterols receptor LXR-alpha,Liver X receptor alpha,Nuclear receptor subfamily 1 group H member 3


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

NR1H3


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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