Human Neuropeptides B/W receptor type 1 (NPBWR1) ELISA Kit
715€ (96 tests)
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name
Human Neuropeptides B/W receptor type 1 (NPBWR1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx535649
tested applications
ELISA
Description
Human Neuropeptides B/W receptor type 1 (NPBWR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Neuropeptides B/W receptor type 1 (NPBWR1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Neuropeptides B/W receptor type 1 (NPBWR1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P48145 |
| Gene ID | 2831 |
| OMIM | 600730 |
| Alias | NPBWR1,GPR7,G protein-coupled receptor 7,neuropeptides B/W receptor type 1 |
| Background | Elisa kits for NPBWR1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
NPBWR1, also known as GPR7, is a G protein-coupled receptor that binds neuropeptide B (NPB) and neuropeptide W (NPW), two endogenous ligands involved in energy regulation, stress, and emotional behaviors. NPBWR1 is predominantly expressed in the central nervous system (CNS), including the hypothalamus, amygdala, and brainstem, where it regulates feeding behavior, stress responses, and neuroendocrine function. Activation of NPBWR1 couples to Gi/o proteins, inhibiting adenylate cyclase activity, which reduces cAMP levels and modulates neuronal excitability. NPBWR1 is implicated in regulating appetite and body weight, as its activation suppresses feeding behavior and influences energy balance. Additionally, NPBWR1 modulates emotional responses, including anxiety and stress-related behaviors, by acting on circuits in the limbic system. Dysregulation of NPBWR1 signaling is linked to obesity, anxiety disorders, and mood dysregulation. Targeting NPBWR1 holds therapeutic potential for metabolic disorders, anxiety, and stress-related conditions due to its role in energy and emotional homeostasis.
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