Human NEO1 (Neogenin) ELISA Kit

Product specifications

ELISA Kits

Human

Colorimetric

4 hours

Sandwich ELISA, Double Antibody

0.156-10ng/ml

0.094ng/ml

96T

ELISA

Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples

Shipped within 10-14 working days.

2-8 °C for 12 months

Q92859

NGN,IGDCC2,NTN1R2, Immunoglobulin superfamily DCC subclass member 2

Elisa kits for NEO1

RUO

Neogenin 1 (NEO1) is a multifunctional transmembrane receptor protein encoded by the NEO1 gene, located on chromosome 15q22.31. It belongs to the immunoglobulin superfamily and is closely related to the Netrin receptors, particularly the Deleted in Colorectal Cancer (DCC) protein. Neogenin 1 plays a pivotal role in a variety of biological processes, including axon guidance, cell migration, apoptosis, and tissue development. Originally identified in neural tissues, NEO1 is now known to be expressed in multiple tissues, indicating its broad biological significance. The receptor is involved in crucial signaling pathways that dictate cell fate and organization during embryonic development and in the adult organism.

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This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq].

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