Human NEO1(Neogenin) ELISA Kit

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name
Human NEO1(Neogenin) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH1782
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | ELISA Kits |
Reactivity | human |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Assay Type | Sandwich ELISA, Double Antibody |
Test Range | 0.156-10ng/ml |
Size 1 | 96T |
Sample Type | Serum,Plasma,Tissue homogenates,Other biological fluids |
Availability | Shipped within 10-14 working days. |
Storage | 2-8 °C for 6 months |
UniProt ID | Q92859 |
Alias | NGN,IGDCC2,NTN1R2, Immunoglobulin superfamily DCC subclass member 2 |
Background | Elisa Kits NEO1 |
Status | RUO |
Neogenin 1 (NEO1) is a multifunctional transmembrane receptor protein encoded by the NEO1 gene, located on chromosome 15q22.31. It belongs to the immunoglobulin superfamily and is closely related to the Netrin receptors, particularly the Deleted in Colorectal Cancer (DCC) protein. Neogenin 1 plays a pivotal role in a variety of biological processes, including axon guidance, cell migration, apoptosis, and tissue development. Originally identified in neural tissues, NEO1 is now known to be expressed in multiple tissues, indicating its broad biological significance. The receptor is involved in crucial signaling pathways that dictate cell fate and organization during embryonic development and in the adult organism.
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This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq].
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