Name: Human Melanin Concentrating Hormone Receptor 2 (MCHR2) ELISA Kit
Brand: Abbexa
SKU: abx250574
Price: 687.5 EUR
Availability: OnlineOnly

Background

MCHR2 is another G protein-coupled receptor for melanin-concentrating hormone (MCH), but unlike MCHR1, it is functionally expressed only in humans and other primates. MCHR2 primarily signals through Gq proteins, activating phospholipase C (PLC) and increasing intracellular calcium levels, which influences neuronal excitability and cellular responses. MCHR2 is expressed in the brain, particularly in regions regulating feeding, energy homeostasis, and mood, where it complements MCHR1’s actions. Activation of MCHR2 stimulates appetite and energy storage, linking it to obesity and metabolic dysregulation. Additionally, MCHR2 is implicated in emotional regulation, with potential roles in stress response and anxiety. Dysregulation of MCHR2 has been associated with overeating and weight gain, making it a target for anti-obesity therapies. Due to its restricted expression in humans and primates, MCHR2 represents a species-specific target with therapeutic potential in metabolic and mood disorders. The development of selective MCHR2 modulators could provide novel approaches to treating obesity and emotional dysregulation.

Características del producto

immunogen target

Melanin Concentrating Hormone Receptor 2 (MCHR2)

reactivity

Human

test range

0.156 ng/ml - 10 ng/ml

assay type

Sandwich

assay data

Quantitative

detection method

Colorimetric

sample type

Tissue homogenates,Cell lysates,Other biological fluids

size 1

96 tests

alias

MCHR2,GPR145,GPRv17,MCH-2R,MCH-R2,MCH2,MCH2R,MCHR-2,SLT,G protein-coupled receptor 145,melanin-concentrating hormone receptor 2

storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit

or code

MCHR2

dry ice

uniprot id

https://www.uniprot.org/uniprotkb/Q969V1

note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

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Human MCHR2(Melanin-concentRating hormone receptor 2) ELISA Kit

proveedor

FineTest

reference

EH1309

reactivity

human

status

RUO

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