Human Mas-related G-protein coupled receptor member X4 (MRGPRX4) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Mas-related G-protein coupled receptor member X4 (MRGPRX4) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx533647
tested applications
ELISA
Description
Human Mas-related G-protein coupled receptor member X4 (MRGPRX4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Mas-related G-protein coupled receptor member X4 (MRGPRX4) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Mas-related G-protein coupled receptor member X4 (MRGPRX4) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q96LA9 |
| OMIM | 607230 |
| Alias | MRGPRX4,SNSR6,MAS-related GPR member X4,Sensory neuron-specific G-protein coupled receptor 6,GPCR,MRGX4 |
| Background | Elisa kits for MRGPRX4 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
MRGPRX4 is another member of the MAS-related G protein-coupled receptor family, and like other MRGPRX receptors, it is involved in mediating sensory and immune responses. It is primarily expressed in mast cells, neurons, and other immune-related tissues. MRGPRX4 plays a role in the regulation of inflammation, particularly in the context of allergic reactions and pain signaling. Upon activation by endogenous ligands such as neuropeptides, MRGPRX4 triggers intracellular signaling that can lead to the release of pro-inflammatory mediators, including histamine. It contributes to the pathogenesis of allergic disorders, such as asthma and atopic dermatitis, as well as conditions associated with chronic pain and neurogenic inflammation. The involvement of MRGPRX4 in these processes makes it an attractive target for drug development aimed at treating allergic conditions, pain disorders, and inflammatory diseases.
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