Human Mas-related G-protein coupled receptor member X4 (MRGPRX4) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for MRGPRX4
proveedor
Abbexareference
abx533647Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Mas-related G-protein coupled receptor member X4 (MRGPRX4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Mas-related G-protein coupled receptor member X4 (MRGPRX4) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
MRGPRX4 is another member of the MAS-related G protein-coupled receptor family, and like other MRGPRX receptors, it is involved in mediating sensory and immune responses. It is primarily expressed in mast cells, neurons, and other immune-related tissues. MRGPRX4 plays a role in the regulation of inflammation, particularly in the context of allergic reactions and pain signaling. Upon activation by endogenous ligands such as neuropeptides, MRGPRX4 triggers intracellular signaling that can lead to the release of pro-inflammatory mediators, including histamine. It contributes to the pathogenesis of allergic disorders, such as asthma and atopic dermatitis, as well as conditions associated with chronic pain and neurogenic inflammation. The involvement of MRGPRX4 in these processes makes it an attractive target for drug development aimed at treating allergic conditions, pain disorders, and inflammatory diseases.
Características del producto
category
ELISA Kits
immunogen target
Mas-related G-protein coupled receptor member X4 (MRGPRX4)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
MRGPRX4,SNSR6,MAS-related GPR member X4,Sensory neuron-specific G-protein coupled receptor 6,GPCR,MRGX4
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
MRGPRX4
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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