Human Mas-related G-protein coupled receptor member X3 (MRGPRX3) ELISA Kit

Este producto es parte de MRGPRX - MAS related GPR family member X
Human Mas-related G-protein coupled receptor member X3 (MRGPRX3) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for MRGPRX3

proveedor

Abbexa

reference

abx533646

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Mas-related G-protein coupled receptor member X3 (MRGPRX3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Mas-related G-protein coupled receptor member X3 (MRGPRX3) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

MRGPRX3 is a member of the MAS-related GPR family of receptors, similar in structure and function to MRGPRX1 and MRGPRX2. It is expressed in sensory neurons and mast cells, playing a role in the mediation of allergic responses and pain. MRGPRX3 is activated by various endogenous peptides and is involved in the release of histamine and other mediators from mast cells, contributing to allergic inflammation. It is particularly involved in the sensation of itch and may also play a role in modulating pain sensitivity and neurogenic inflammation. The receptor’s activation leads to the initiation of intracellular signaling cascades that include calcium release and other pro-inflammatory responses. Dysregulation of MRGPRX3 signaling is linked to disorders involving chronic pain, itch, and hypersensitivity. As a potential therapeutic target, MRGPRX3 could be modulated for the treatment of chronic pain conditions, allergic disorders, and inflammatory diseases.

Características del producto

category

ELISA Kits


immunogen target

Mas-related G-protein coupled receptor member X3 (MRGPRX3)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

MRGPRX3,MrgA,Mrgpra,Mrga10,SNSR1,Sensory neuron-specific G protein-coupled receptor 1,GPCR,MRGX3,SNSR1,SNSR2


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

MRGPRX3


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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