Human Mas-related G-protein coupled receptor member X3 (MRGPRX3) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Mas-related G-protein coupled receptor member X3 (MRGPRX3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx533646
tested applications
ELISA
Description
Human Mas-related G-protein coupled receptor member X3 (MRGPRX3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Mas-related G-protein coupled receptor member X3 (MRGPRX3) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Mas-related G-protein coupled receptor member X3 (MRGPRX3) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q96LB0 |
| OMIM | 607229 |
| Alias | MRGPRX3,MrgA,Mrgpra,Mrga10,SNSR1,Sensory neuron-specific G protein-coupled receptor 1,GPCR,MRGX3,SNSR1,SNSR2 |
| Background | Elisa kits for MRGPRX3 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
MRGPRX3 is a member of the MAS-related GPR family of receptors, similar in structure and function to MRGPRX1 and MRGPRX2. It is expressed in sensory neurons and mast cells, playing a role in the mediation of allergic responses and pain. MRGPRX3 is activated by various endogenous peptides and is involved in the release of histamine and other mediators from mast cells, contributing to allergic inflammation. It is particularly involved in the sensation of itch and may also play a role in modulating pain sensitivity and neurogenic inflammation. The receptor’s activation leads to the initiation of intracellular signaling cascades that include calcium release and other pro-inflammatory responses. Dysregulation of MRGPRX3 signaling is linked to disorders involving chronic pain, itch, and hypersensitivity. As a potential therapeutic target, MRGPRX3 could be modulated for the treatment of chronic pain conditions, allergic disorders, and inflammatory diseases.
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