Human Lysophosphatidic Acid Receptor 2 (LPAR2) ELISA Kit

Este producto es parte de LPAR - Lysophosphatidic Acid Receptor
Human Lysophosphatidic Acid Receptor 2 (LPAR2) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for LPAR2

proveedor

Abbexa

reference

abx531251

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Lysophosphatidic Acid Receptor 2 (LPAR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Lysophosphatidic Acid Receptor 2 (LPAR2) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

LPAR2 is a G protein-coupled receptor for lysophosphatidic acid (LPA), expressed predominantly in epithelial tissues, the gastrointestinal tract, and immune cells. LPAR2 activation triggers signaling through Gq, Gi, and G12/13 proteins, leading to phospholipase C (PLC) activation, calcium mobilization, and Rho-mediated cytoskeletal changes. LPAR2 regulates cell proliferation, migration, and survival, playing important roles in tissue repair, immune responses, and cancer progression. In wound healing, LPAR2 promotes epithelial cell migration and proliferation, aiding tissue regeneration. In cancer, LPAR2 signaling enhances tumor cell survival, invasion, and resistance to apoptosis, particularly in ovarian and gastrointestinal cancers. LPAR2 also modulates immune responses by regulating cytokine production and immune cell migration. Dysregulation of LPAR2 is associated with inflammatory diseases and cancer metastasis. Targeting LPAR2 with selective antagonists is being explored for treating cancers and inflammatory conditions, as it contributes to pathological cell growth, migration, and survival.

Características del producto

category

ELISA Kits


immunogen target

Lysophosphatidic Acid Receptor 2 (LPAR2)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

LPAR2,EDG4,LPA2,EDG-4,LPA-2,Pbx4,pre-B-cell leukemia transcription factor 4,endothelial differentiation gene 4,lysophosphatidic acid G-protein-coupled receptor 4


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

LPAR2


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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