Human Leucine Rich Repeat In FLII Interacting Protein 1 (LRRFIP1) CLIA Kit
845€ (96 tests)
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name
Human Leucine Rich Repeat In FLII Interacting Protein 1 (LRRFIP1) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx495526
tested applications
CLIA
Description
Human Leucine Rich Repeat In FLII Interacting Protein 1 (LRRFIP1) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Leucine Rich Repeat In FLII Interacting Protein 1 (LRRFIP1) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.127 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | LRR FLII-interacting protein 1,GC-binding factor 2,GCF2, TRIP,GCF2; TRIP; FLAP1; GCF-2; FLAP-1; HUFI-1; FLIIAP1 |
| Background | CLIA Kits LRRFIP1 |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Leucine-rich repeat flightless-interacting protein 1 (LRRFIP1) is a multifunctional protein implicated in various cellular processes, including transcriptional regulation, immune response modulation, and cytoskeletal organization. LRRFIP1 binds to transcription factors and regulates their activity, acting as a co-activator or repressor depending on the cellular context. Its role in innate immunity is highlighted by its interaction with the Toll-like receptor signaling pathway, where it influences the expression of pro-inflammatory cytokines such as IL-6 and TNF-alpha. Additionally, LRRFIP1 plays a role in actin cytoskeleton remodeling through its interaction with flightless I, a member of the gelsolin family. Dysregulation of LRRFIP1 expression or function has been associated with various pathological conditions, including cancer and autoimmune diseases. Studies have also identified its involvement in the Wnt signaling pathway, further emphasizing its significance in cellular proliferation and differentiation.
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