Human Leucine-rich repeat-containing protein 16C (CARMIL2) ELISA Kit
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Descripción del producto
Human Leucine-rich repeat-containing protein 16C (CARMIL2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Leucine-rich repeat-containing protein 16C (CARMIL2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Especificaciones del producto
| Alias | LRRC16C, RLTPR,Leucine-rich repeat-containing protein 16C,F-actin-uncapping protein RLTPR |
| Assay Data | Quantitative |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Background | Elisa kits for CARMIL2 |
| Category | ELISA Kits |
| Detection Method | Colorimetric |
| Dry Ice | No |
| Form | Lyophilized |
| Immunogen Target | Leucine-rich repeat-containing protein 16C (CARMIL2) |
| Name | Human Leucine-rich repeat-containing protein 16C (CARMIL2) ELISA Kit |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
| Price | 715 |
| Provider | Abbexa |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Reference | abx531321 |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Size 1 | 96 tests |
| Status | RUO |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Tested Applications | ELISA |
| UniProt ID | Q6F5E8 |
Descripcion del producto en español
Background en español
CARMIL2, also known as RLTPR, regulates actin cytoskeleton dynamics and is involved in T cell activation and immune synapse formation. It functions by interacting with capping proteins to modulate actin polymerization, enabling proper immune cell signaling and migration. CARMIL2 is crucial for T cell receptor signaling and NF-kB activation, making it essential for adaptive immune responses. Mutations or dysregulation of CARMIL2 are associated with immune deficiencies and autoimmune diseases. Research into CARMIL2 focuses on its role in cytoskeletal remodeling and immune synapse assembly, with potential therapeutic implications in immunodeficiency disorders.
Related Products
RLTPR / CARMIL2 Antibody
RLTPR/CARMIL2 Antibody is a Mouse Monoclonal against RLTPR/CARMIL2. This gene encodes a member of the CARMIL (capping protein, Arp2/3, myosin-I linker) family of proteins. The encoded protein interacts with and negatively regulates the heterodimeric capping protein and promotes cell migration. Reduced expression of this gene has been observed in human psoriasis patients. Mutations in this gene cause a human immunodeficiency syndrome characterized by smooth muscle tumors and impaired T-cell function. [provided by RefSeq, May 2017]. RLTPR / CARMIL2 is a cytosolic protein, which with high affinity binds CAPZA2 (capping protein muscle actin Z-line alpha 2) and decreases CAPZA2 affinity for actin barbed ends.
Ver Producto
RLTPR / CARMIL2 Antibody
RLTPR/CARMIL2 Antibody is a Mouse Monoclonal against RLTPR/CARMIL2.
Ver ProductoCapping protein, Arp2/3 and myosin-I linker protein 2 (CARMIL2) Antibody
Capping protein, Arp2/3 and myosin-I linker protein 2 (CARMIL2) Antibody is a Rabbit Polyclonal antibody for the detection of Human CARMIL2.
Ver Producto