Human Leucine-rich repeat-containing protein 16C (CARMIL2) ELISA Kit
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Description
Human Leucine-rich repeat-containing protein 16C (CARMIL2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Leucine-rich repeat-containing protein 16C (CARMIL2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Leucine-rich repeat-containing protein 16C (CARMIL2) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q6F5E8 |
| Alias | LRRC16C, RLTPR,Leucine-rich repeat-containing protein 16C,F-actin-uncapping protein RLTPR |
| Background | Elisa kits for CARMIL2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
CARMIL2, also known as RLTPR, regulates actin cytoskeleton dynamics and is involved in T cell activation and immune synapse formation. It functions by interacting with capping proteins to modulate actin polymerization, enabling proper immune cell signaling and migration. CARMIL2 is crucial for T cell receptor signaling and NF-kB activation, making it essential for adaptive immune responses. Mutations or dysregulation of CARMIL2 are associated with immune deficiencies and autoimmune diseases. Research into CARMIL2 focuses on its role in cytoskeletal remodeling and immune synapse assembly, with potential therapeutic implications in immunodeficiency disorders.
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