Capping protein, Arp2/3 and myosin-I linker protein 2 (CARMIL2) Antibody

Este producto es parte de CARMIL - Capping protein, Arp2/3 and myosin-I linker
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169€ (20 µl)

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935106861
info@markelab.com
name
Capping protein, Arp2/3 and myosin-I linker protein 2 (CARMIL2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx346582
tested applications
ELISA, WB, IP

Description

Capping protein, Arp2/3 and myosin-I linker protein 2 (CARMIL2) Antibody is a Rabbit Polyclonal antibody for the detection of Human CARMIL2.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Capping protein, Arp2/3 and myosin-I linker protein 2 (CARMIL2)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G chromatography.
Size 1
20 µl
Size 2
50 µl
Size 3
100 µl
Size 4
200 µl
Size 5
1 ml
Form
Liquid
Tested Applications
ELISA, WB, IP
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q6F5E8
Alias
LRRC16C, RLTPR,Leucine-rich repeat-containing protein 16C,F-actin-uncapping protein RLTPR
Background
Antibody anti-CARMIL2
Status
RUO

Descripción

CARMIL2, also known as RLTPR, regulates actin cytoskeleton dynamics and is involved in T cell activation and immune synapse formation. It functions by interacting with capping proteins to modulate actin polymerization, enabling proper immune cell signaling and migration. CARMIL2 is crucial for T cell receptor signaling and NF-kB activation, making it essential for adaptive immune responses. Mutations or dysregulation of CARMIL2 are associated with immune deficiencies and autoimmune diseases. Research into CARMIL2 focuses on its role in cytoskeletal remodeling and immune synapse assembly, with potential therapeutic implications in immunodeficiency disorders.

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