Human Interleukin 22 (IL22) Protein

Este producto es parte de IL22 - interleukin 22
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715€ (50 µg)

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935106861
info@markelab.com
name
Human Interleukin 22 (IL22) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx651527
tested applications
WB, SDS-PAGE

Description

Interleukin 22 (IL22) Protein is a Human protein produced in 293F cell.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Interleukin 22 (IL22)
Host
293F cell
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 18.4 kDa  Observed MW: 22 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Ala34-Ile179
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 97%
Size 1
50 µg
Size 2
100 µg
Size 3
200 µg
Size 4
500 µg
Size 5
1 mg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9GZX6
Alias
TIFa,IL-21,IL-22,ILTIF,IL-TIF,IL-D110,zcyto18,TIFIL-23,Cytokine Zcyto18,IL-10-related T-cell-derived-inducible factor IL-TIF,
Background
Protein IL22
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Interleukin 22 (IL22) is a cytokine that belongs to the IL-10 family of cytokines. It plays a critical role in the innate and adaptive immune systems, particularly at epithelial barriers such as the skin, lungs, intestines, and liver. IL-22 is unique in that it primarily targets non-hematopoietic cells (e.g., epithelial cells) rather than immune cells. It promotes tissue protection, regeneration, and defense against pathogens, particularly in the context of infections and inflammatory diseases. IL-22 is primarily produced by a subset of CD4+ T cells, including Th17, Th22 cells, natural killer (NK) cells, and innate lymphoid cells (ILCs). The role of IL-22 is highly context-dependent. While it contributes to maintaining epithelial integrity and promoting tissue repair, excessive or chronic IL-22 production can exacerbate inflammatory diseases, such as psoriasis, inflammatory bowel disease (IBD), and rheumatoid arthritis (RA).

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