Human Interferon alpha 21 (IFNa21) ELISA Kit
715€ (96 tests)
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name
Human Interferon alpha 21 (IFNa21) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx152002
tested applications
ELISA
Description
Human Interferon alpha 21 (IFNa21) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Interferon alpha 21 (IFNa21) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Interferon Alpha 21 (IFNa21)
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Interferon alpha 21 (IFNa21) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 15.62 pg/ml - 1000 pg/ml |
| Sensitivity | < 6.2 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P01568 |
| Alias | LeIF F,leIF-F,IFN-alphaI,IFN-alpha-21,Interferon alpha-F |
| Background | Elisa kits for IFNA21 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Interferon Alpha 21 (IFNA21) is another crucial component of the type I interferon family, known for its role in innate and adaptive immunity. IFNA21 is rapidly upregulated in response to viral infections and pathogen-associated molecular patterns (PAMPs) recognized by Toll-like receptors and other sensors. It exerts its effects by binding to IFNAR, which activates downstream signaling pathways, including the JAK-STAT cascade, resulting in the induction of interferon-stimulated genes. These genes coordinate various antiviral mechanisms, such as inhibiting viral protein synthesis, degrading viral RNA, and upregulating major histocompatibility complex (MHC) molecules for enhanced antigen presentation. IFNA21 also plays a role in modulating the immune response by activating NK cells and promoting the differentiation and survival of cytotoxic T cells. Its functional specificity compared to other interferons, such as differences in potency or tissue-specific expression, underscores the complexity of the interferon system in orchestrating effective immune defenses against pathogens. Further investigations into IFNA21's unique properties could reveal novel therapeutic opportunities for infectious and immune-mediated diseases.
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