Human Immunoglobulin Superfamily Containing Leucine-Rich Repeat Protein (ISLR) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Immunoglobulin Superfamily Containing Leucine-Rich Repeat Protein (ISLR) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx152064
tested applications
ELISA
Description
Human Immunoglobulin Superfamily Containing Leucine-Rich Repeat Protein (ISLR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Immunoglobulin Superfamily Containing Leucine Rich Repeat Protein (ISLR) concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Immunoglobulin Superfamily Containing Leucine Rich Repeat Protein (ISLR)
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Immunoglobulin Superfamily Containing Leucine-Rich Repeat Protein (ISLR) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.07 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | Meflin,HsT17563 |
| Background | Elisa kits for ISLR |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ISLR, also known as matrilin-4-related protein, is a secreted protein that belongs to the immunoglobulin superfamily and features leucine-rich repeat (LRR) domains. It is widely expressed in mesenchymal tissues, including those involved in the extracellular matrix (ECM) and connective tissue remodeling. ISLR plays a role in regulating cell adhesion, tissue repair, and fibroblast activation. ISLR is critical for maintaining the structural integrity of the ECM and facilitating tissue remodeling during processes such as wound healing and organ fibrosis. It interacts with integrins and other ECM components to modulate cellular signaling and promote mesenchymal cell differentiation. Dysregulation of ISLR has been implicated in fibrotic diseases, tumor progression, and metastasis, where it influences ECM dynamics and cell migration.
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