Human Hemicentin 1 (HMCN1) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits HMCN1
proveedor
Abbexareference
abx387823Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Hemicentin 1 (HMCN1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human HMCN1 concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Background
Hemicentin 1 (HMCN1) is a large extracellular matrix protein that belongs to the fibulin family and is characterized by its multiple immunoglobulin (Ig)-like and epidermal growth factor (EGF)-like domains. It is primarily involved in the maintenance of tissue architecture and cell adhesion processes. HMCN1 is widely expressed in tissues such as the eyes, skin, and kidneys, where it contributes to basement membrane stability and the organization of extracellular structures. Mutations in the HMCN1 gene have been associated with age-related macular degeneration (AMD), suggesting a critical role in retinal integrity and function. In addition, HMCN1 is implicated in cancer biology, where its dysregulation has been linked to altered tumor microenvironments and metastatic potential. The protein’s interactions with integrins and other ECM components underline its importance in cell signaling and tissue homeostasis, making it a significant focus in studies on tissue repair, fibrosis, and oncogenesis.
Características del producto
category
ELISA Kits
immunogen target
Hemicentin 1 (HMCN1)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.06 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
ARMD1,FBLN6,FIBL6,FIBL-6,Fibulin-6
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
HMCN1
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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