Human Hemicentin 1 (HMCN1) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human Hemicentin 1 (HMCN1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx387823
tested applications
ELISA
Description
Human Hemicentin 1 (HMCN1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human HMCN1 concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Hemicentin 1 (HMCN1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q96RW7 |
| Gene ID | 83872 |
| OMIM | 603075 |
| Alias | ARMD1,FBLN6,FIBL6,FIBL-6,Fibulin-6 |
| Background | Elisa kits for HMCN1 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Hemicentin 1 (HMCN1) is a large extracellular matrix protein that belongs to the fibulin family and is characterized by its multiple immunoglobulin (Ig)-like and epidermal growth factor (EGF)-like domains. It is primarily involved in the maintenance of tissue architecture and cell adhesion processes. HMCN1 is widely expressed in tissues such as the eyes, skin, and kidneys, where it contributes to basement membrane stability and the organization of extracellular structures. Mutations in the HMCN1 gene have been associated with age-related macular degeneration (AMD), suggesting a critical role in retinal integrity and function. In addition, HMCN1 is implicated in cancer biology, where its dysregulation has been linked to altered tumor microenvironments and metastatic potential. The protein’s interactions with integrins and other ECM components underline its importance in cell signaling and tissue homeostasis, making it a significant focus in studies on tissue repair, fibrosis, and oncogenesis.
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