Human GRB2-associated-binding protein 4 (GAB4) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for GAB4
proveedor
Abbexareference
abx524641Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human GRB2-associated-binding protein 4 (GAB4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human GRB2-associated-binding protein 4 (GAB4) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Background
GAB4 is a lesser-characterized member of the GAB family, sharing structural similarity with GAB1, GAB2, and GAB3. It acts as an adaptor protein that recruits signaling molecules like PI3K and SHP2 to receptor tyrosine kinases, activating pathways such as PI3K/Akt and MAPK. GAB4 is expressed in various tissues, including immune and epithelial cells, where it regulates cell adhesion, migration, and proliferation. Though its biological role is not as well-studied, GAB4 is suggested to contribute to immune responses, cellular differentiation, and signal transduction. Dysregulation of GAB4 may influence tumor progression and immune dysfunction, but further research is needed to elucidate its specific roles and mechanisms.
Características del producto
category
ELISA Kits
immunogen target
GRB2-associated-binding protein 4 (GAB4)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
size 1
96 tests
alias
GRB2-associated binder 2-like ,GAB2-like,GRB2-associated binder 4
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
GAB4
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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