GAB4 Antibody
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935106861
info@markelab.com
Precio
52€ (10 µg)
Antibody anti-GAB4
proveedor
Abbexareference
abx249441Tested Applications
IHCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
GAB4 Antibody is a Rabbit Polyclonal against GAB4.
Background
GAB4 is a lesser-characterized member of the GAB family, sharing structural similarity with GAB1, GAB2, and GAB3. It acts as an adaptor protein that recruits signaling molecules like PI3K and SHP2 to receptor tyrosine kinases, activating pathways such as PI3K/Akt and MAPK. GAB4 is expressed in various tissues, including immune and epithelial cells, where it regulates cell adhesion, migration, and proliferation. Though its biological role is not as well-studied, GAB4 is suggested to contribute to immune responses, cellular differentiation, and signal transduction. Dysregulation of GAB4 may influence tumor progression and immune dysfunction, but further research is needed to elucidate its specific roles and mechanisms.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
GAB4
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
IHC
purification
Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
recommended dilution
Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
size 1
10 µg
size 2
100 µg
size 3
200 µg
size 4
300 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
GAB4
dry ice
No
availability
Shipped within 5-10 working days.
alias
GRB2-associated binder 2-like ,GAB2-like,GRB2-associated binder 4
note
Concentration: 1 mg/ml -
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