Human G-protein coupled receptor 42 (GPR42) ELISA Kit
715€ (96 tests)
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935106861
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name
Human G-protein coupled receptor 42 (GPR42) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx526031
tested applications
ELISA
Description
Human G-protein coupled receptor 42 (GPR42) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human G-protein coupled receptor 42 (GPR42) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | G-protein coupled receptor 42 (GPR42) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O15529 |
| Gene ID | 2866 |
| OMIM | 603822 |
| Alias | GPR42,FFAR1L,GPR41L,FFAR3L,G protein-coupled receptor 42 (gene/pseudogene),FFAR1L,GPR42P |
| Background | Elisa kits for GPR42 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
GPR42 is a G protein-coupled receptor closely related to free fatty acid receptor 3 (FFAR3/GPR41). It binds short-chain fatty acids (SCFAs) such as acetate, propionate, and butyrate, which are produced by gut microbiota during the fermentation of dietary fibers. GPR42 is primarily expressed in the gastrointestinal tract and adipose tissue, where it regulates energy metabolism, gut hormone secretion, and immune responses. Although its function is similar to FFAR3, GPR42 is considered a pseudogene in some individuals due to genetic variations that can inactivate its function. When active, GPR42 modulates SCFA-mediated signaling pathways, influencing insulin sensitivity, appetite regulation, and energy expenditure. Dysregulation of GPR42 signaling is associated with metabolic disorders like obesity and type 2 diabetes, where impaired SCFA signaling disrupts metabolic homeostasis. Its involvement in linking gut microbiota activity with host metabolism highlights GPR42 as a potential target for therapeutic interventions aimed at improving metabolic health and reducing obesity-related diseases.
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