Human Fructose-Bisphosphate Aldolase A (ALDOA) Protein
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935106861
info@markelab.com
Precio
234€ (5 µg)
Protein ALDOA
proveedor
Abbexareference
abx073104Tested Applications
SDS-PAGEreactivity
status
RUOclonality
Descripción
Human Aldolase-A is a recombinant protein expressed in E. coli.
Background
ALDOA is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate into glyceraldehyde-3-phosphate and dihydroxyacetone phosphate during glycolysis. It is widely expressed, particularly in muscle tissues and the brain, where it plays a crucial role in energy metabolism and ATP production. ALDOA is vital for providing energy to rapidly proliferating cells and tissues with high metabolic demands. Dysregulation of ALDOA has been associated with cancer progression, as elevated glycolytic activity (Warburg effect) fuels tumor growth. Mutations in ALDOA cause glycogen storage disease type XII, characterized by hemolytic anemia and muscle weakness due to impaired glycolytic flux. Its role in energy metabolism underscores its importance in cellular homeostasis, growth, and disease.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Fructose-Bisphosphate Aldolase A (ALDOA)
host
E. coli
form
Liquid
tested applications
SDS-PAGE
size 1
5 µg
size 2
20 µg
size 3
1 mg
observerd MW
Molecular Weight: 41.5 kDa Concentration: 1 mg/ml Sequence Fragment: 1-364 AA. Tag: N-terminal His tag
expression
Recombinant
purity
> 95% (SDS-PAGE)
purification
Purified by proprietary chromatographic techniques.
recommended dilution
Optimal dilutions/concentrations should be determined by the end user.
buffer
20 mM Tris-HCl buffer, pH 8.0, containing 0.1 M NaCl and 10% glycerol.
storage
Store at 4 °C if the entire vial will be used within 4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles.
or code
ALDOA
dry ice
No
availability
Shipped within 5-10 working days.
alias
ALDOA,ALDA
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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