Human Fc receptor-like protein 4 (FCRL4) ELISA Kit
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935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits FCRL4
proveedor
Abbexareference
abx523756Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Fc receptor-like protein 4 (FCRL4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Fc receptor-like protein 4 (FCRL4) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Fc Receptor Like 4 (FCRL4) is a transmembrane protein expressed on a subset of memory B cells, predominantly in mucosal and inflamed tissues. Unlike other Fc receptor-like proteins, FCRL4 has a distinct role in dampening B cell receptor (BCR) signaling. It contains immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in its cytoplasmic tail, allowing it to inhibit activation signals and antibody production. FCRL4 expression is often upregulated in chronic infections and autoimmune diseases, where it is associated with an exhausted B cell phenotype, potentially contributing to immune dysregulation and impaired humoral responses.
Características del producto
category
ELISA Kits
immunogen target
Fc receptor-like protein 4 (FCRL4)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
Fc receptor-like protein 4,FCRH4,IGFP2,IRTA1,CD307d,FcR-like protein 4,FcRL4,IFGP family protein 2,hIFGP2
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
FCRL4
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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