Human Fc receptor-like protein 4 (FCRL4) ELISA Kit

Este producto es parte de FCRL - Fc receptor like
Human Fc receptor-like protein 4 (FCRL4) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

687.5€ (96 tests)

Elisa Kits FCRL4

proveedor

Abbexa

reference

abx523756

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Fc receptor-like protein 4 (FCRL4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Fc receptor-like protein 4 (FCRL4) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Fc Receptor Like 4 (FCRL4) is a transmembrane protein expressed on a subset of memory B cells, predominantly in mucosal and inflamed tissues. Unlike other Fc receptor-like proteins, FCRL4 has a distinct role in dampening B cell receptor (BCR) signaling. It contains immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in its cytoplasmic tail, allowing it to inhibit activation signals and antibody production. FCRL4 expression is often upregulated in chronic infections and autoimmune diseases, where it is associated with an exhausted B cell phenotype, potentially contributing to immune dysregulation and impaired humoral responses.

Características del producto

category

ELISA Kits


immunogen target

Fc receptor-like protein 4 (FCRL4)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


alias

Fc receptor-like protein 4,FCRH4,IGFP2,IRTA1,CD307d,FcR-like protein 4,FcRL4,IFGP family protein 2,hIFGP2


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

FCRL4


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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