Fc Receptor-Like Protein 4 (FCRL4) Antibody (FITC)
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935106861
info@markelab.com
Precio
162.5€ (20 µg)
Antibody anti-FCRL4
proveedor
Abbexareference
abx309174Tested Applications
reactivity
Humanstatus
RUOclonality
PolyclonalDescripción
FCRL4 Antibody (FITC) is a Rabbit Polyclonal against FCRL4 conjugated to FITC.
Background
Fc Receptor Like 4 (FCRL4) is a transmembrane protein expressed on a subset of memory B cells, predominantly in mucosal and inflamed tissues. Unlike other Fc receptor-like proteins, FCRL4 has a distinct role in dampening B cell receptor (BCR) signaling. It contains immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in its cytoplasmic tail, allowing it to inhibit activation signals and antibody production. FCRL4 expression is often upregulated in chronic infections and autoimmune diseases, where it is associated with an exhausted B cell phenotype, potentially contributing to immune dysregulation and impaired humoral responses.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Fc Receptor-Like Protein 4 (FCRL4)
host
Rabbit
conjugation
FITC
form
Liquid
purity
> 95%
purification
Purified by Protein G.
buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
size 1
20 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
or code
FCRL4
dry ice
No
availability
Shipped within 5-10 working days.
alias
Fc receptor-like protein 4,FCRH4,IGFP2,IRTA1,CD307d,FcR-like protein 4,FcRL4,IFGP family protein 2,hIFGP2
uniprot id
NCBI accession
NP_112572.1, NM_031282.2
note
This product is for research use only.
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