Human Ezrin (EZR) CLIA Kit
845€ (96 tests)
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935106861
info@markelab.com
name
Human Ezrin (EZR) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx492606
tested applications
CLIA
Description
Human Cytovillin Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Ezrin (EZR) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.117 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | CVL,CVIL,VIL2,HEL-S-105,Cytovillin,Villin-2 |
| Background | CLIA Kits EZR |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Ezrin (EZR) is a protein that serves as a linker between the plasma membrane and the actin cytoskeleton, playing a key role in maintaining cell shape, motility, and signaling EZR is involved in various cellular processes such as cell adhesion, migration, and the formation of membrane protrusions like microvilli It functions by connecting actin filaments to membrane proteins, facilitating signal transduction and helping to organize cell structures involved in processes like phagocytosis and endocytosis Ezrin is highly expressed in cells such as epithelial cells, neurons, and immune cells, where it plays a crucial role in tissue development, synaptic function, and immune responses Dysregulation of EZR activity is linked to various diseases, including cancer, where aberrant ezrin function contributes to tumor cell metastasis and invasion Additionally, EZR is involved in maintaining the integrity of the blood-brain barrier and regulating synaptic plasticity in neurons, making it essential for both neurological and immune functions
