Human Docking Protein 5 (DOK5) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Docking Protein 5 (DOK5) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx386971
tested applications
ELISA
Description
Human Docking Protein 5 (DOK5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DOK5 concentrations in serum, plasma and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Docking Protein 5 (DOK5) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.094 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9P104 |
| Gene ID | 55816 |
| OMIM | 608334 |
| Alias | Downstream of tyrosine kinase 5,C20orf180,IRS-6,IRS6,Insulin receptor substrate 6 |
| Background | Elisa kits for DOK5 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
DOK5 is a member of the DOK family, functioning as an adaptor protein in signaling pathways downstream of RET and insulin receptors. It is expressed in skeletal muscle, heart, and nervous tissue, where it regulates processes like cell survival, differentiation, and metabolic signaling. DOK5 enhances insulin signaling by activating the MAPK/ERK pathway but does not influence the PI3K/Akt pathway. It is critical for neurite outgrowth and neuronal development, particularly in response to neurotrophic factors. Dysregulation of DOK5 contributes to insulin resistance and is implicated in neurological disorders, where it affects neuronal survival and axonal guidance.
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