Human Docking Protein 5 (DOK5) ELISA Kit

Este producto es parte de DOK - Docking protein
Human Docking Protein 5 (DOK5) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for DOK5

proveedor

Abbexa

reference

abx386971

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Docking Protein 5 (DOK5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DOK5 concentrations in serum, plasma and other biological fluids.


Background

DOK5 is a member of the DOK family, functioning as an adaptor protein in signaling pathways downstream of RET and insulin receptors. It is expressed in skeletal muscle, heart, and nervous tissue, where it regulates processes like cell survival, differentiation, and metabolic signaling. DOK5 enhances insulin signaling by activating the MAPK/ERK pathway but does not influence the PI3K/Akt pathway. It is critical for neurite outgrowth and neuronal development, particularly in response to neurotrophic factors. Dysregulation of DOK5 contributes to insulin resistance and is implicated in neurological disorders, where it affects neuronal survival and axonal guidance.

Características del producto

category

ELISA Kits


immunogen target

Docking Protein 5 (DOK5)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.094 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma and other biological fluids.


size 1

96 tests


alias

Downstream of tyrosine kinase 5,C20orf180,IRS-6,IRS6,Insulin receptor substrate 6


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

DOK5


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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