Name: Docking Protein 5 (DOK5) Antibody
Brand: Abbexa
SKU: abx013823
Price: 43.75 EUR
Availability: OnlineOnly

Background

DOK5 is a member of the DOK family, functioning as an adaptor protein in signaling pathways downstream of RET and insulin receptors. It is expressed in skeletal muscle, heart, and nervous tissue, where it regulates processes like cell survival, differentiation, and metabolic signaling. DOK5 enhances insulin signaling by activating the MAPK/ERK pathway but does not influence the PI3K/Akt pathway. It is critical for neurite outgrowth and neuronal development, particularly in response to neurotrophic factors. Dysregulation of DOK5 contributes to insulin resistance and is implicated in neurological disorders, where it affects neuronal survival and axonal guidance.

Características del producto

clonality

Polyclonal

reactivity

Human, Mouse

immunogen target

Docking Protein 5 (DOK5)

host

Rabbit

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB

purification

Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.

buffer

PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.

size 1

10 µg

size 2

100 µg

size 3

200 µg

size 4

300 µg

size 5

1 mg

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

DOK5

dry ice

availability

Shipped within 5-10 working days.

alias

Downstream of tyrosine kinase 5,C20orf180,IRS-6,IRS6,Insulin receptor substrate 6

uniprot id

https://www.uniprot.org/uniprotkb/Q9P104

note

This product is for research use only.

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anti- DOK5 antibody

proveedor

FineTest

reference

FNab02504

Tested Applications

ELISA, WB

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly o...

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