Human Coronin 1C (CORO1C) ELISA Kit

Este producto es parte de CORO - Coronin
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Coronin 1C (CORO1C) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx386641
tested applications
ELISA

Description

Human Coronin 1C (CORO1C) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human CORO1C concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetCoronin 1C (CORO1C)
ReactivityHuman
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich
Test Range0.156 ng/ml - 10 ng/ml
Sensitivity< 0.094 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-12 working days. The validity for this kit is 6 months.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDQ9ULV4
Gene ID23603
OMIM605269
AliasHCRNN4,Coronin-3,Coronin-1C,CRN2,CRNN4
BackgroundElisa kits for CORO1C
StatusRUO
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Coronin 1C (CORO1C) is another member of the coronin protein family with a role in regulating actin filament dynamics. Like CORO1A and CORO1B, CORO1C plays a crucial role in cellular processes such as actin-based movement, endocytosis, and cytokinesis. However, CORO1C is particularly important in the regulation of the immune system, where it modulates the signaling pathways of immune cells, including T cells, and contributes to the response to inflammation. It is also involved in maintaining the structural integrity of immune synapses, which are crucial for the communication between immune cells. Similar to the other coronins, CORO1C's dysregulation can impair immune function and has been associated with conditions that affect immune responses. Understanding the role of CORO1C in immune cell signaling and actin dynamics is critical for advancing therapeutic strategies targeting immune-related diseases.

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