Human Contactin-5 (CNTN5) ELISA Kit

Este producto es parte de CNTN - contactin
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Contactin-5 (CNTN5) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx507699
tested applications
ELISA

Description

Human Contactin-5 (CNTN5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Contactin-5 (CNTN5) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetContactin-5 (CNTN5)
ReactivityHuman
Detection MethodColorimetric
Assay DataQuantitative
Test Range0.156 ng/ml - 10 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-15 working days. The validity for this kit is 6 months.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDO94779
Gene ID53942
OMIM607219
AliasNB-2,HNB-2s,Neural recognition molecule NB-2,Contactin-5
BackgroundElisa kits for CNTN5
StatusRUO
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Contactin 5 (CNTN5), also known as NB-2, is a neural cell adhesion molecule that plays a significant role in synaptic organization, axon guidance, and neuronal communication. CNTN5 is primarily expressed in the central and peripheral nervous systems, particularly in sensory and auditory neurons, where it contributes to the formation of functional neural circuits. It mediates interactions with other adhesion molecules and receptors, influencing synaptic stability and plasticity. CNTN5 is linked to neurodevelopmental conditions, including autism and intellectual disability, as genetic variations affecting CNTN5 expression have been associated with altered brain connectivity and cognitive deficits. Its expression pattern is developmentally regulated, with high levels during embryonic stages that decrease postnatally. Structurally, CNTN5 shares the conserved immunoglobulin-like and fibronectin type III domains of the contactin family, enabling it to mediate diverse adhesive and signaling interactions crucial for nervous system function.

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