Human Contactin 3 (CNTN3) Protein (Active)
1079€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Contactin 3 (CNTN3) Protein (Active)
category
Proteins and Peptides
provider
Abbexa
reference
abx691022
tested applications
SDS-PAGE
Description
Human Contactin 3 Protein is a recombinant protein from Human produced in HEK293 Cells. A DNA sequence encoding the human CNTN3 precursor (NP_065923.1) (Met 1-Ser 1002, 708 Asp/Asn) was expressed with the fused Fc region of human IgG1 at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Contactin 3 |
| Host | HEK293 cells |
| Origin | Human |
| Observed MW | Molecular Weight: 134.5 kDa Sequence Fragment: Met1-Ser1002, 708 Asp/Asn Tag: C-terminal Fc tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile 100mM Glycine, 10mM NaCl, 50mM Tris, pH 7.5. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NP_065923.1 |
| Alias | PCS,PANG,BIG-1,KIAA1496,Plasmacytoma-associated neuronal glycoprotein,Brain-derived immunoglobulin superfamily protein 1,Contactin-3 |
| Background | Protein CNTN3 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Contactin 3 (CNTN3), also known as BIG-1, is a neural adhesion molecule that belongs to the contactin family and is primarily expressed in the brain, particularly in areas involved in learning and memory, such as the hippocampus and cortex. CNTN3 mediates cell-cell adhesion and axonal interactions, contributing to synaptic formation and plasticity. It interacts with other neuronal receptors and adhesion molecules to regulate axon guidance and neuronal migration during development. CNTN3 has been implicated in neurodevelopmental disorders, including autism spectrum disorders and schizophrenia, where its dysregulation disrupts synaptic connectivity and neural circuit function. Its expression is developmentally regulated, with high levels observed during embryonic and early postnatal stages. Structurally, CNTN3 features immunoglobulin and fibronectin type III domains, facilitating homophilic and heterophilic interactions that are essential for its role in neural development. Emerging research suggests that CNTN3 may also have a role in neurodegenerative diseases and brain plasticity, though its exact mechanisms remain under investigation.
Related Products
Mouse Contactin 3 (CNTN3) Protein
Recombinant Contactin 3 (CNTN3) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Ver Producto
Contactin 3 (CNTN3) Antibody
Contactin 3 (CNTN3) Antibody is a Rabbit Polyclonal antibody for the detection of Contactin 3 (CNTN3).
Ver Producto