Human Centromere protein X (CENPX) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human Centromere protein X (CENPX) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx506231
tested applications
ELISA
Description
Human Centromere protein X (CENPX) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Centromere protein X (CENPX) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Centromere protein X (CENPX) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | A8MT69 |
| Gene ID | 201254 |
| OMIM | 615128 |
| Alias | FAAP10,MHF2,STRA13,CENP-X,D9 |
| Background | Elisa kits for CENPX |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
STRA13, also known as CENPX, is a member of the basic helix-loop-helix (bHLH) family of transcription factors. STRA13 is upregulated in response to retinoic acid, hypoxia, and other cellular stress signals, where it functions as a transcriptional repressor or activator depending on its interaction partners. It regulates processes such as cell cycle progression, apoptosis, immune responses, and metabolic pathways. STRA13 plays a crucial role in hypoxia-inducible factor (HIF)-mediated responses by suppressing cell proliferation and modulating oxygen-dependent pathways. It is highly expressed in immune cells, cancer tissues, and hypoxic environments, where it controls inflammatory cytokine production and enhances cellular survival under low oxygen. Dysregulation of STRA13 is associated with cancer progression, immune dysregulation, and metabolic disorders. Loss-of-function studies reveal defects in immune regulation, impaired response to hypoxia, and abnormal cell proliferation, emphasizing its role in stress adaptation, transcriptional regulation, and homeostasis maintenance.
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