Human Cadherin EGF LAG Seven Pass G-Type Receptor 2 (CELSR2) ELISA Kit
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Cadherin EGF LAG Seven Pass G-Type Receptor 2 (CELSR2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx151030
tested applications
ELISA
Description
Human Cadherin EGF LAG Seven Pass G-Type Receptor 2 (CELSR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Cadherin EGF LAG Seven Pass G-Type Receptor 2 (CELSR2) concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Cadherin EGF LAG Seven Pass G-Type Receptor 2 (CELSR2)
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Cadherin EGF LAG Seven Pass G-Type Receptor 2 (CELSR2) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.07 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | CELSR2,ADGRC2,MEGF3,multiple epidermal growth factor-like domains 3,CDHF10,Flamingo1 |
| Background | Elisa kits for CELSR2 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
CELSR2 encodes Cadherin EGF LAG seven-pass G-type receptor 2, another member of the adhesion GPCR family that functions in the regulation of cell polarity and neuronal migration. CELSR2 is a key component of the Wnt/planar cell polarity (PCP) signaling pathway, coordinating neuronal guidance and proper axon outgrowth during brain development. CELSR2 is predominantly expressed in the developing brain, particularly in regions like the cerebral cortex, where it governs synapse formation and neuronal connectivity. Mutations in CELSR2 have been associated with neurodevelopmental disorders, including autism spectrum disorder (ASD) and intellectual disability, as disruptions in PCP signaling can impair brain structure and function. CELSR2 has also been identified in genome-wide studies as a gene linked to coronary artery disease (CAD) and lipid metabolism, particularly low-density lipoprotein cholesterol (LDL-C) regulation. Beyond its role in development, CELSR2 contributes to tissue regeneration and cancer progression, where it can influence epithelial-mesenchymal transition (EMT) and cell invasion. CELSR2's cadherin and EGF-like domains mediate both cell adhesion and intercellular signaling, making it critical for both normal development and disease states.
Related Products
Cadherin EGF LAG Seven Pass G-Type Receptor 2 (CELSR2) Antibody
CELSR2 Antibody is a Rabbit Polyclonal antibody against Human.
Ver Producto
Human Cadherin EGF LAG Seven Pass G-Type Receptor 2 (CELSR2) Protein
Recombinant Cadherin EGF LAG Seven Pass G-Type Receptor 2 (CELSR2) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Ver Producto
Cadherin EGF LAG Seven Pass G-Type Receptor 2 (CELSR2) Antibody
Polyclonal Antibody to Cadherin EGF LAG Seven Pass G-Type Receptor 2 (CELSR2).
Ver Producto