Human Cadherin EGF LAG seven-pass G-type receptor 1 (CELSR1) ELISA Kit
715€ (96 tests)
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name
Human Cadherin EGF LAG seven-pass G-type receptor 1 (CELSR1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx506145
tested applications
ELISA
Description
Human Cadherin EGF LAG seven-pass G-type receptor 1 (CELSR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Cadherin EGF LAG seven-pass G-type receptor 1 (CELSR1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Cadherin EGF LAG seven-pass G-type receptor 1 (CELSR1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9NYQ6 |
| Alias | CELSR1,ADGRC1,ME2,FMI2,CDHF9,HFMI2,ADGRC1,LMPHM9 |
| Background | Elisa kits for CELSR1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
CELSR1 encodes the Cadherin EGF LAG seven-pass G-type receptor 1, a member of the adhesion GPCR (G-protein coupled receptor) family. CELSR1 is integral to the non-canonical Wnt/planar cell polarity (PCP) pathway, which regulates tissue polarity and cell orientation during development. It is expressed widely in developing tissues, particularly in the nervous system, skin, and vascular endothelium. CELSR1 plays a significant role in processes like neural tube closure, ensuring proper spinal cord formation. Mutations in CELSR1 are associated with neural tube defects such as spina bifida and craniorachischisis, conditions caused by the failure of the neural tube to close. In addition to its developmental role, CELSR1 is involved in angiogenesis, where it supports endothelial cell alignment during blood vessel formation. CELSR1's extracellular domains contain cadherin repeats, which mediate cell-cell adhesion, and EGF-like domains that influence cell signaling. Dysregulation of CELSR1 has been implicated in cancer metastasis, where it contributes to the loss of cell polarity and enhanced cell migration. CELSR1 is therefore of interest for its roles in embryonic development, wound healing, and disease pathogenesis, particularly in oncology and developmental biology.
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CELSR1 Antibody is a Rabbit Polyclonal against CELSR1.
Ver ProductoCadherin EGF LAG Seven-Pass G-Type Receptor 1 (CELSR1) Antibody
Cadherin EGF LAG Seven-Pass G-Type Receptor 1 (CELSR1) Antibody is a Rabbit Polyclonal antibody for the detection of Human CELSR1.
Ver ProductoCadherin EGF LAG Seven-Pass G-Type Receptor 1 (CELSR1) Antibody (HRP)
Cadherin EGF LAG Seven-Pass G-Type Receptor 1 (CELSR1) Antibody (HRP) is a Rabbit Polyclonal antibody conjugated to HRP for the detection of Human CELSR1.
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