Human Bone Marrow Stromal Antigen 2 (BST2) Protein
234€ (2 µg)
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Name
Human Bone Marrow Stromal Antigen 2 (BST2) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx262367
Tested Applications
SDS-PAGE
Description
Bone Marrow Stromal Cell Antigen 2 Protein is a recombinant cytokine.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | BST2 |
| Assay Type | Activity: Not tested |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 80% (SDS-PAGE) |
| Size 1 | 2 µg |
| Size 2 | 10 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | Q10589 |
| Alias | CD317,HM1.24,TETHERIN,HM1.24 antigen |
| Background | Protein BST2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Bone Marrow Stromal Cell Antigen 2 (BST2), also known as tetherin, is a type II transmembrane protein that plays a significant role in the immune response. It is involved in antiviral defenses, specifically by restricting the release of enveloped viruses from infected cells. BST2 was first identified on bone marrow stromal cells, but it is now known to be expressed broadly across different cell types, especially in immune cells, including B cells, dendritic cells, and monocytes. Its antiviral function is key for innate immunity, as BST2 restricts viruses like HIV, Ebola, and others by physically tethering budding virions to the cell surface, preventing their release into the extracellular environment where they can infect new cells. BST2 is also implicated in various physiological processes beyond viral restriction, including immune signaling, cell adhesion, and tumor development. Its expression is upregulated by interferons, a group of cytokines involved in immune signaling, which is indicative of its role in responding to infections and potentially other stressors within the body.
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