Bone Marrow Stromal Antigen 2 (BST2) Antibody
52€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Bone Marrow Stromal Antigen 2 (BST2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx119589
Tested Applications
WB
Description
BST2 Antibody is a Rabbit Polyclonal antibody against BST2.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Bone Marrow Stromal Antigen 2 (BST2) Immunogen: Immunogen is Internal. H. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q10589 |
| Alias | CD317,HM1.24,TETHERIN,HM1.24 antigen |
| Background | Antibody anti-BST2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Bone Marrow Stromal Cell Antigen 2 (BST2), also known as tetherin, is a type II transmembrane protein that plays a significant role in the immune response. It is involved in antiviral defenses, specifically by restricting the release of enveloped viruses from infected cells. BST2 was first identified on bone marrow stromal cells, but it is now known to be expressed broadly across different cell types, especially in immune cells, including B cells, dendritic cells, and monocytes. Its antiviral function is key for innate immunity, as BST2 restricts viruses like HIV, Ebola, and others by physically tethering budding virions to the cell surface, preventing their release into the extracellular environment where they can infect new cells. BST2 is also implicated in various physiological processes beyond viral restriction, including immune signaling, cell adhesion, and tumor development. Its expression is upregulated by interferons, a group of cytokines involved in immune signaling, which is indicative of its role in responding to infections and potentially other stressors within the body.
Productos relacionados
Bone Marrow Stromal Antigen 2 (BST2) Antibody
BST2 Antibody is a Rabbit Polyclonal antibody against BST2. Bone marrow stromal cells are involved in the growth and dev…
Ver producto Bone Marrow Stromal Cell Antigen 2 (BST2) Antibody
Bone Marrow Stromal Cell Antigen 2 Antibody is a Rabbit Polyclonal antibody against Bone Marrow Stromal Cell Antigen 2.…
Ver producto Bone Marrow Stromal Antigen 2 (BST2) Antibody
BST2 Antibody is a Rabbit Polyclonal antibody against BST2.…
Ver producto