Human Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 (GCNT4) ELISA Kit

Este producto es parte de GCNT - glucosaminyl (N-acetyl) transferase
Human Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 (GCNT4) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

687.5€ (96 tests)

Elisa Kits GCNT4

proveedor

Abbexa

reference

abx525010

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 (GCNT4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 (GCNT4) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Glucosaminyl (N-acetyl) transferase 4 (GCNT4) is a glycosyltransferase enzyme responsible for catalyzing the formation of core 2 O-glycans, critical components of glycoproteins and mucins involved in cellular adhesion, signaling, and epithelial protection GCNT4 is expressed primarily in the gastrointestinal tract, pancreas, and other mucin-secreting tissues where it contributes to the maintenance of epithelial integrity and mucus production Studies have shown that GCNT4 plays a role in regulating glycoprotein branching, which is essential for cell surface interactions and immune responses Dysregulation of GCNT4 has been linked to colorectal and pancreatic cancers, where altered glycosylation promotes tumor growth, metastasis, and resistance to apoptosis Furthermore, GCNT4 expression is modulated during inflammatory conditions, impacting mucosal defense and contributing to diseases like ulcerative colitis and Crohn’s disease Emerging evidence highlights its role in epithelial homeostasis and its potential as a biomarker for gastrointestinal diseases and therapeutic target for cancer treatment

Características del producto

category

ELISA Kits


immunogen target

Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 (GCNT4)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


alias

Core 2-branching enzyme 3,Core2-GlcNAc-transferase 3,C2GnT3,LINC01338


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

GCNT4


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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