Human ATP Binding Cassette Transporter E1 (ABCE1) Protein
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Description
Human ABCE1 Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | ATP Binding Cassette Transporter E1 (ABCE1) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 22.4 kDa Observed MW (SDS-PAGE): 22 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ile389-Asn556 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 100 mM NaHCO<sub>3</sub>, 500 mM NaCl, pH 8.3, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P61221 |
| Alias | ABC38,OABP,RLI,RLI1,RNASEL1 |
| Background | Protein ABCE1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ABCE1, also known as the ATP-binding cassette protein E1 or RNase L inhibitor (RLI), is a unique member of the ATP-binding cassette (ABC) transporter superfamily. Unlike most ABC transporters, which are involved in the translocation of various substrates across membranes, ABCE1 primarily functions in the regulation of RNA processing and translation. It is highly conserved across different species, highlighting its fundamental biological importance.ABCE1 works by inhibiting the activity of ribonuclease L, thereby opposing the antiviral properties of ribonuclease L and enabling the virus to synthesize viral proteins. Additionally, ABCE1 has been implicated in influencing tumor cell proliferation
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