anti- ABCE1 antibody

Descripción

Antagonizes the binding of 2-5A(5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly.

Características del producto

clonality

polyclonal

reactivity

human

immunogen target

ATP-binding cassette, sub-family E(OABP), member 1

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB, IHC

observerd MW

50-70 kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

ABCE1

alias

ABC38,OABP,RLI,RLI1,RNASEL1

uniprot id

https://www.uniprot.org/uniprotkb/P61221

gene id

https://www.ncbi.nlm.nih.gov/gene/6059

note

This product is for research use only.

Quizá le pueda interesar