ATP Binding Cassette Subfamily E Member 1 (ABCE1) Antibody
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Description
ABCE1 Antibody is a Rabbit Polyclonal Antibody against ABCE1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ATP Binding Cassette Subfamily E Member 1 (ABCE1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P61221 |
| Gene ID | 6059 |
| NCBI Accession | NP_002931.2 |
| Alias | ABC38,OABP,RLI,RLI1,RNASEL1 |
| Background | Antibody anti-ABCE1 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
ABCE1, also known as the ATP-binding cassette protein E1 or RNase L inhibitor (RLI), is a unique member of the ATP-binding cassette (ABC) transporter superfamily. Unlike most ABC transporters, which are involved in the translocation of various substrates across membranes, ABCE1 primarily functions in the regulation of RNA processing and translation. It is highly conserved across different species, highlighting its fundamental biological importance.ABCE1 works by inhibiting the activity of ribonuclease L, thereby opposing the antiviral properties of ribonuclease L and enabling the virus to synthesize viral proteins. Additionally, ABCE1 has been implicated in influencing tumor cell proliferation
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