Human ATP Binding Cassette Subfamily F Member 2 (ABCF2) Protein

Este producto es parte de ABCF - ATP Binding Cassette Transporter F
Human ATP Binding Cassette Subfamily F Member 2 (ABCF2) Protein

Pida mas información

935106861

info@markelab.com

Precio

208€ (10 µg)

Protein ABCF2

proveedor

Abbexa

reference

abx650391

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Human ABCF2 Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).


Background

ABCF2 is an atypical ATP-binding cassette protein that lacks transmembrane domains, functioning in intracellular processes such as cellular stress response and protein homeostasis. It is expressed in various tissues, with notable activity in the liver and kidneys, where it may protect cells from oxidative damage and environmental toxins. ABCF2 is believed to interact with the ubiquitin-proteasome system, regulating protein degradation and turnover, which is critical for maintaining cellular proteostasis under stress conditions. Recent evidence suggests that ABCF2 may also play a role in cancer, contributing to tumor progression and survival by modulating stress response pathways and protein stability. Its involvement in cellular adaptation to metabolic and oxidative stress underscores its importance in maintaining cell viability and function. Dysregulation of ABCF2 has been linked to resistance to chemotherapeutic agents, further emphasizing its potential as a therapeutic target. Despite growing evidence of its roles, further research is needed to elucidate its precise mechanisms in cellular metabolism and disease.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

ATP Binding Cassette Subfamily F Member 2 (ABCF2)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 29.9 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ile396-Val623 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ABCF2


dry ice

No


availability

Shipped within 5-7 working days.


alias

ABC28,HUSSY-18,HUSSY18


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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