Human ATP Binding Cassette Subfamily F Member 2 (ABCF2) Protein
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935106861
info@markelab.com
Precio
208€ (10 µg)
Protein ABCF2
proveedor
Abbexareference
abx650391Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Human ABCF2 Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Background
ABCF2 is an atypical ATP-binding cassette protein that lacks transmembrane domains, functioning in intracellular processes such as cellular stress response and protein homeostasis. It is expressed in various tissues, with notable activity in the liver and kidneys, where it may protect cells from oxidative damage and environmental toxins. ABCF2 is believed to interact with the ubiquitin-proteasome system, regulating protein degradation and turnover, which is critical for maintaining cellular proteostasis under stress conditions. Recent evidence suggests that ABCF2 may also play a role in cancer, contributing to tumor progression and survival by modulating stress response pathways and protein stability. Its involvement in cellular adaptation to metabolic and oxidative stress underscores its importance in maintaining cell viability and function. Dysregulation of ABCF2 has been linked to resistance to chemotherapeutic agents, further emphasizing its potential as a therapeutic target. Despite growing evidence of its roles, further research is needed to elucidate its precise mechanisms in cellular metabolism and disease.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
ATP Binding Cassette Subfamily F Member 2 (ABCF2)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 29.9 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ile396-Val623 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
ABCF2
dry ice
No
availability
Shipped within 5-7 working days.
alias
ABC28,HUSSY-18,HUSSY18
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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