Human Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 (AGAP3) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 (AGAP3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501269
tested applications
ELISA
Description
Human Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 (AGAP3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 (AGAP3) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 (AGAP3) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q96P47 |
| Alias | AGAP-3,CENTG3,CRAG |
| Background | Elisa kits for AGAP3 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AGAP3 is a multifunctional protein involved in vesicle trafficking, cytoskeletal organization, and intracellular signaling pathways. Structurally, it contains a GTPase-activating protein (GAP) domain, ankyrin repeats, and a pleckstrin homology (PH) domain, which mediate its interactions with small GTPases, particularly Arf proteins, and enable membrane association. AGAP3 plays a role in endosomal transport, receptor recycling, and the regulation of cytoskeletal dynamics, with a particular impact on processes like cell migration and neuronal signaling. It is expressed in various tissues, including the nervous system, where it influences synaptic plasticity and vesicle formation. Dysregulation of AGAP3 has been implicated in cancer progression, as it enhances cell motility and survival, and in neurological disorders where it affects cellular transport and signaling.
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