Human Anterior Gradient Protein 2 (AGR2) ELISA Kit
611€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Anterior Gradient Protein 2 (AGR2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx251981
tested applications
ELISA
Description
Human Anterior Gradient Protein 2 (AGR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Anterior Gradient Protein 2 (AGR2) concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Anterior Gradient Protein 2 (AGR2) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | 0.1 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O95994 |
| Alias | AG-2,AG2,GOB-4,HAG-2,HEL-S-116,HPC8 |
| Background | Elisa kits for AGR2 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AGR2 is a protein involved in the endoplasmic reticulum (ER) stress response and functions as a protein disulfide isomerase (PDI), facilitating the proper folding of secreted and membrane proteins. It is primarily expressed in secretory tissues such as the gastrointestinal tract, lungs, and prostate, where it maintains ER homeostasis by catalyzing the formation of disulfide bonds in proteins. AGR2 also plays a role in cell adhesion and migration, partly through its interaction with mucins like MUC1 and MUC2. Overexpression of AGR2 is frequently observed in cancers, including breast, pancreatic, and prostate cancers, where it contributes to tumor progression, chemoresistance, and metastasis by promoting cell survival under stress conditions
Related Products
Human AGR2(Anterior Gradient Protein 2) ELISA Kit
Ver Producto
Mouse Agr2(Anterior gradient protein 2 homolog) ELISA Kit
Ver Producto
anti- AGR2 antibody
Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells(By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth.
Ver Producto