Human Annexin A8 (ANXA8) Protein
1235€ (100 µg)
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name
Human Annexin A8 (ANXA8) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx693190
tested applications
SDS-PAGE
Description
Human Annexin A8 Protein is a recombinant protein from Human produced in E. coli. A DNA sequence encoding the human ANXA8 (AAH73755.1) (Met1-Pro327) was expressed with a polyhistidine tag at the N-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Annexin A8 |
| Host | E. coli |
| Origin | Human |
| Observed MW | Molecular Weight: 39.1 kDa Sequence Fragment: Met1-Pro327 Tag: N-terminal His tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | AAH73755.1 |
| Alias | ANXA8,ANX8 |
| Background | Protein ANXA8 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ANXA8 is a member of the annexin family with calcium-dependent phospholipid-binding activity, predominantly expressed in epithelial tissues and certain immune cells. ANXA8 is involved in processes such as cell membrane organization, vesicle transport, and signal transduction. Its overexpression has been observed in cancers such as breast cancer and acute myeloid leukemia (AML), where it is associated with drug resistance, cell proliferation, and metastasis. ANXA8 has been implicated in angiogenesis and inflammation, where it regulates endothelial cell behavior and cytokine signaling. Its role in promoting tumorigenesis and its expression in pathological conditions make it a potential biomarker and target for therapeutic intervention in cancer and inflammatory diseases.
