Annexin A8 (ANXA8) Antibody
364€ (100 µg)
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935106861
info@markelab.com
name
Annexin A8 (ANXA8) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx230440
tested applications
ELISA, WB, IHC
Description
Annexin VIII Antibody is a Rabbit Polyclonal against Annexin VIII.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Annexin A8 (ANXA8) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/200 - 1/1000, IHC: 1/50 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P13928 |
| Alias | ANXA8,ANX8 |
| Background | Antibody anti-ANXA8 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
ANXA8 is a member of the annexin family with calcium-dependent phospholipid-binding activity, predominantly expressed in epithelial tissues and certain immune cells. ANXA8 is involved in processes such as cell membrane organization, vesicle transport, and signal transduction. Its overexpression has been observed in cancers such as breast cancer and acute myeloid leukemia (AML), where it is associated with drug resistance, cell proliferation, and metastasis. ANXA8 has been implicated in angiogenesis and inflammation, where it regulates endothelial cell behavior and cytokine signaling. Its role in promoting tumorigenesis and its expression in pathological conditions make it a potential biomarker and target for therapeutic intervention in cancer and inflammatory diseases.
