Annexin A8 (ANXA8) Antibody
357.5€ (100 µg)
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Name
Annexin A8 (ANXA8) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx037069
Tested Applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the ANXA8 protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Annexin A8 (ANXA8) Immunogen: Recombinant fragment corresponding to 158-326 AA of human ANXA8. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 37 kDa |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | ANXA8,ANX8 |
| Background | Antibody anti-ANXA8 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ANXA8 is a member of the annexin family with calcium-dependent phospholipid-binding activity, predominantly expressed in epithelial tissues and certain immune cells. ANXA8 is involved in processes such as cell membrane organization, vesicle transport, and signal transduction. Its overexpression has been observed in cancers such as breast cancer and acute myeloid leukemia (AML), where it is associated with drug resistance, cell proliferation, and metastasis. ANXA8 has been implicated in angiogenesis and inflammation, where it regulates endothelial cell behavior and cytokine signaling. Its role in promoting tumorigenesis and its expression in pathological conditions make it a potential biomarker and target for therapeutic intervention in cancer and inflammatory diseases.
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