Human Annexin A3 (ANXA3) Protein
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935106861
info@markelab.com
Precio
234€ (10 µg)
Protein ANXA3
proveedor
Abbexareference
abx065369Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant Annexin A3 (ANXA3) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Background
ANXA3 is a calcium- and phospholipid-binding protein that regulates membrane trafficking, signal transduction, and inflammatory responses. It is expressed in various tissues, including immune and endothelial cells, and plays a role in angiogenesis and immune cell function. ANXA3 regulates phospholipase A2 (PLA2) activity, influencing arachidonic acid metabolism and eicosanoid production during inflammation. Dysregulation of ANXA3 has been associated with drug resistance in cancer cells, particularly in ovarian and colorectal cancers, where it enhances tumor cell survival and chemoresistance. Its involvement in immune responses and tumor progression underscores its significance as a potential biomarker and therapeutic target.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Annexin A3 (ANXA3)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 15.7 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Trp190-Glu312 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
ANXA3
dry ice
No
availability
Shipped within 5-12 working days.
alias
ANXA3,ANX3,Annexin-3,Lipocortin III
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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