Human Alpha-protein kinase 2 (ALPK2) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human Alpha-protein kinase 2 (ALPK2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501587
tested applications
ELISA
Description
Human Alpha-protein kinase 2 (ALPK2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Alpha-protein kinase 2 (ALPK2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Alpha-protein kinase 2 (ALPK2) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q86TB3 |
| Alias | ALPK2,HAK |
| Background | Elisa kits for ALPK2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ALPK2 is a member of the alpha-protein kinase family, a group of atypical serine/threonine kinases that phosphorylate substrates in regions of alpha-helical structures. ALPK2 is primarily expressed in epithelial tissues, where it is involved in processes such as cellular signaling, proliferation, and stress responses. Recent studies indicate that ALPK2 plays a significant role in inflammation and tumorigenesis. Its upregulation has been observed in colorectal and gastric cancers, suggesting a link between ALPK2 and cancer progression through its ability to activate pro-inflammatory pathways, such as NF-κB signaling. By promoting cytokine production and immune cell recruitment, ALPK2 may facilitate chronic inflammation, which contributes to tumor microenvironment remodeling. Additionally, ALPK2 is believed to influence epithelial-mesenchymal transition (EMT), a critical step in cancer metastasis. Dysregulation of ALPK2 may also impact cellular homeostasis, making it a potential biomarker for gastrointestinal cancers and inflammatory diseases.
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