Human Allograft Inflammatory Factor 1 (AIF1) Protein
234€ (2 µg)
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935106861
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name
Human Allograft Inflammatory Factor 1 (AIF1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx262211
tested applications
SDS-PAGE
Description
Allograft Inflammatory Factor 1 Protein is a cytokine.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Allograft Inflammatory Factor 1 (AIF1) |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 2 µg |
| Size 2 | 10 µg |
| Size 3 | 1 mg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | P55008 |
| Gene ID | 199 |
| OMIM | 601833 |
| Alias | AIF-1,IBA1,IRT-1,IRT1 |
| Background | Protein AIF1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
AIF1 is an inflammation-responsive protein primarily expressed in macrophages, microglia, and other immune cells. It plays a critical role in immune regulation, particularly in modulating inflammatory responses, cell migration, and phagocytosis. Structurally, AIF1 contains EF-hand calcium-binding motifs, enabling it to respond to changes in intracellular calcium levels, which are key to immune cell activation and signaling. AIF1 is upregulated during inflammatory diseases such as autoimmune disorders, transplant rejection, and atherosclerosis, where it contributes to immune cell recruitment and tissue remodeling. It is also involved in promoting macrophage activation and migration to sites of injury or infection. Dysregulated AIF1 expression is associated with chronic inflammation, cancer progression, and neuroinflammatory diseases like multiple sclerosis, making it a potential biomarker and therapeutic target for inflammatory and immune-related disorders.
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