Human Agmatine Ureohydrolase (AGMAT) Protein
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935106861
info@markelab.com
Precio
247€ (10 µg)
Protein AGMAT
proveedor
Abbexareference
abx065196Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant Agmatine Ureohydrolase (AGMAT) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Background
Agmatinase (AGMAT) is a mitochondrial enzyme involved in polyamine biosynthesis, catalyzing the conversion of agmatine into putrescine, a precursor for spermidine and spermine. These polyamines are crucial for cellular growth, DNA stabilization, protein translation, and stress adaptation. AGMAT is expressed in diverse tissues, including the brain, liver, and kidney, and it plays a central role in regulating neuronal health, liver detoxification, and cellular stress responses. Dysregulation of AGMAT affects polyamine homeostasis and has been linked to neurodegenerative disorders, including Alzheimer’s disease, due to its influence on oxidative stress and synaptic signaling. In cancer, AGMAT expression supports rapid cell division by enhancing polyamine levels, making it a potential biomarker and therapeutic target. Additionally, AGMAT’s role in modulating inflammatory pathways is being explored, as polyamines influence immune cell activity and cytokine production.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Agmatine Ureohydrolase (AGMAT)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 42.3 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Pro53-Ala151 Tag: N-terminal His tag and GST tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
AGMAT
dry ice
No
availability
Shipped within 5-12 working days.
alias
AGMAT
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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