Human Agmatine Ureohydrolase (AGMAT) Protein

Este producto es parte de AGMAT - Agmatinase Mitochondrial l Elisa - Clia - Antibody - Protein
Human Agmatine Ureohydrolase (AGMAT) Protein

Pida mas información

935106861

info@markelab.com

Precio

247€ (10 µg)

Protein AGMAT

proveedor

Abbexa

reference

abx065196

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant Agmatine Ureohydrolase (AGMAT) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).


Background

Agmatinase (AGMAT) is a mitochondrial enzyme involved in polyamine biosynthesis, catalyzing the conversion of agmatine into putrescine, a precursor for spermidine and spermine. These polyamines are crucial for cellular growth, DNA stabilization, protein translation, and stress adaptation. AGMAT is expressed in diverse tissues, including the brain, liver, and kidney, and it plays a central role in regulating neuronal health, liver detoxification, and cellular stress responses. Dysregulation of AGMAT affects polyamine homeostasis and has been linked to neurodegenerative disorders, including Alzheimer’s disease, due to its influence on oxidative stress and synaptic signaling. In cancer, AGMAT expression supports rapid cell division by enhancing polyamine levels, making it a potential biomarker and therapeutic target. Additionally, AGMAT’s role in modulating inflammatory pathways is being explored, as polyamines influence immune cell activity and cytokine production.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Agmatine Ureohydrolase (AGMAT)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 42.3 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Pro53-Ala151 Tag: N-terminal His tag and GST tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

AGMAT


dry ice

No


availability

Shipped within 5-12 working days.


alias

AGMAT


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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