Human AGMAT (Agmatinase, mitochondrial) ELISA Kit

Este producto es parte de AGMAT - Agmatinase Mitochondrial l Elisa - Clia - Antibody - Protein
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935106861
info@markelab.com
name
Human AGMAT (Agmatinase, mitochondrial) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH1578
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Human
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
0.781-50ng/ml
Sensitivity
0.469ng/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
Q9BSE5
Alias
AGMAT
Background
Elisa kits for AGMAT
Status
RUO

Agmatinase (AGMAT) is a mitochondrial enzyme involved in polyamine biosynthesis, catalyzing the conversion of agmatine into putrescine, a precursor for spermidine and spermine. These polyamines are crucial for cellular growth, DNA stabilization, protein translation, and stress adaptation. AGMAT is expressed in diverse tissues, including the brain, liver, and kidney, and it plays a central role in regulating neuronal health, liver detoxification, and cellular stress responses. Dysregulation of AGMAT affects polyamine homeostasis and has been linked to neurodegenerative disorders, including Alzheimer’s disease, due to its influence on oxidative stress and synaptic signaling. In cancer, AGMAT expression supports rapid cell division by enhancing polyamine levels, making it a potential biomarker and therapeutic target. Additionally, AGMAT’s role in modulating inflammatory pathways is being explored, as polyamines influence immune cell activity and cytokine production.

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