Human Adenylate Cyclase 1, Brain (ADCY1) Protein
234€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Human Adenylate Cyclase 1, Brain (ADCY1) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx166977
Tested Applications
WB, SDS-PAGE
Description
Human Adenylate Cyclase 1, Brain Protein is a recombinant Human protein expressed in E. coli.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Adenylate Cyclase 1, Brain (ADCY1) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Arg835-Asn1061 Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 29.3 kDa Observed MW (SDS-PAGE): 29 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 100 mM NaHCO<sub>3</sub>, 500 mM NaCl, pH 8.3, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| Alias | AC1,DFNB44,ATP pyrophosphate-lyase 1 |
| Background | Protein ADCY1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in ddH2O to a concentration between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Background
ADCY1 is a membrane-bound enzyme predominantly expressed in the brain, specifically in neuronal tissues. It is activated by G-protein-coupled receptors (GPCRs) and regulated by calcium/calmodulin, playing a vital role in generating cyclic AMP (cAMP), a second messenger critical for signal transduction. ADCY1 is essential for synaptic plasticity, learning, and memory processes. Dysregulation of ADCY1 has been linked to neurological disorders, such as cognitive impairments and epilepsy, due to impaired cAMP signaling pathways. Its expression and activity are crucial for calcium-dependent cAMP production in neurons.
Productos relacionados
Adenylate Cyclase 1, Brain (ADCY1) Antibody
Rabbit polyclonal antibody against ADCY1 protein. Immunogen region is Internal.…
Ver producto
Adenylate Cyclase 1, Brain (ADCY1) Antibody
Adenylate Cyclase 1 (Brain) Antibody is a Rabbit Polyclonal antibody against Adenylate Cyclase 1 (Brain).…
Ver producto
Adenylate Cyclase 1, Brain (ADCY1) Antibody
ADCY1 Antibody is a Rabbit Polyclonal Antibody against ADCY1.…
Ver producto