Adenylate Cyclase 1, Brain (ADCY1) Antibody

Este producto es parte de ADCY - Adenylate Cyclase Type
Adenylate Cyclase 1, Brain (ADCY1) Antibody

Pida mas información

935106861

info@markelab.com

Precio

43.75€ (10 µg)

Antibody anti-ADCY1

proveedor

Abbexa

reference

abx013894

Tested Applications

ELISA, WB

reactivity

Human, Mouse

status

RUO

clonality

Polyclonal

Descripción

Rabbit polyclonal antibody against ADCY1 protein. Immunogen region is Internal.


Background

ADCY1 is a membrane-bound enzyme predominantly expressed in the brain, specifically in neuronal tissues. It is activated by G-protein-coupled receptors (GPCRs) and regulated by calcium/calmodulin, playing a vital role in generating cyclic AMP (cAMP), a second messenger critical for signal transduction. ADCY1 is essential for synaptic plasticity, learning, and memory processes. Dysregulation of ADCY1 has been linked to neurological disorders, such as cognitive impairments and epilepsy, due to impaired cAMP signaling pathways. Its expression and activity are crucial for calcium-dependent cAMP production in neurons.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human, Mouse


immunogen target

Adenylate Cyclase 1, Brain (ADCY1)


host

Rabbit


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, WB


purification

Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.


buffer

PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.


size 1

10 µg


size 2

100 µg


size 3

200 µg


size 4

300 µg


size 5

1 mg


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

ADCY1


dry ice

No


availability

Shipped within 5-10 working days.


alias

AC1,DFNB44,ATP pyrophosphate-lyase 1


note

This product is for research use only.


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43.75€ (10 µg)

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